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（2026）Huijberts | 使用 PCCT 显示豆纹动脉
在这项回顾性队列研究中，共纳入159 例蛛网膜下腔出血患者，与常规 EID-CTA 相比，超高分辨率（UHR）PCCT 显著改善了豆纹动脉（LSA）的显示效果。对于起自距大脑中动脉（MCA）起点 >5 mm 处的分支，PCCT 的检出率接近 DSA——例如，左半球中观察者 1 的检出率分别为 93% 和 85%（p = 0.62）；而 EID-CTA 在非配对比较中仅检出49%。 在显示较大 LSA 分支的完整远端范围方面，PCCT 仍不如 DSA。观察者 1 测得的、距 MCA 起点 >5 mm 的 LSA 中位长度为PCCT 上为 23 mm，DSA 上为 40 mm；不过，PCCT 显示的可测量分支仍显著长于 EID-CTA（23…
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(2026) Hellms | Non-gated pediatric cardiac PCCT cuts dose while preserving image quality
In 37 children with congenital heart disease matched to 37 EID-CT controls by water-equivalent diameter, non-ECG-gated high-pitch PCCT substantially reduced radiation exposure: CTDIvol 0.20 ± 0.12 vs 0.37 ± 0.17 mGy and DLP 4.06 ± 3.22 vs 7.21 ± 4.67 mGy·cm (p < 0.001 for both), corresponding to roughly 46% and 44%…
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(2026) Volovici | UHR PCCT pure-lumen imaging for neurosurgical navigation
In this selected pilot cohort of 20 complex neurosurgical cases, UHR PCCT provided additional anatomical information beyond conventional MRI/CT, particularly for arterial anatomy (11/20, 55%), tumor vascular supply (7/20, 35%), venous anatomy (6/20, 30%), and skull-base/orbital/osseous involvement (8/20, 40%). The greatest…
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A massive primary cerebral ALK-positive anaplastic large cell lymphoma in an adolescent
Xiangyu Liu, RT*; Jiaxu Wei, RT*; Xi Zhao, MD**; Ji Wang, RT* * Department of Radiology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, P. R. China** Siemens Healthineers, China 2025-07-02 Download pdf History A 15-year-old male patient, complaining of a growing lump on the right of…
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(2026) Nishii | Optimization of the kernel for temporal bone imaging in PCCT
This study combined physical phantom testing of 11 UHR reconstruction kernels (Hr60–Hr98) with clinical visual assessment in 12 patients / 24 temporal bones. Physically, increasing kernel sharpness improved spatial resolution but increased high-frequency noise: Hr96 achieved the highest measured resolution, whereas Hr60…
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PCCT for coronary assessment and functional imaging in Takotsubo cardiomyopathy
@Bálint Szilveszter, Borbála Vattay, Péter Csongor, @Milan Vecsey-Nagy Városmajor Heart and Vascular Centre, Cardiac CT Working Group, Budapest, Hungary September 29, 2026 https://siemens-healthineers.bynder.com/asset/a85e1bdc-bf2b-4a4d-94a0-dc890f0a7651/CT-NAEOTOM-CONNECT-CaseReport-Takutsobu-2-VIDEO-2026.mp4…
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PCCT for myocardial tissue characterization in acute myocarditis: comparison with CMR
Ferenc Imre Suhai, Barbara Sipos, Milán Vecsey-Nagy, Bálint Szilveszter Városmajor Heart and Vascular Centre, Cardiac CT Working Group, Budapest, Hungary September 29, 2026 https://siemens-healthineers.bynder.com/asset/2a67d11b-415e-4e25-a74a-42d82ff7a4d5/CT-NAEOTOM-CONNECT-CaseReport-BalintMyocard-1-VIDEO-2026.mp4…
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(2026) Hyska | Time-resolved PCCT estimates post-TAVI pressure gradients
In 71 post-TAVI PCCT examinations from 63 patients, time-resolved cardiac PCCT enabled calculation of prosthetic-valve hemodynamics from left-ventricular volumetry and direct valve-orifice planimetry. CT-derived mean and maximum transvalvular gradients correlated strongly with echocardiography (ρ = 0.85 for both), while…
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(2026) Pali | PCCT iodine maps quantify when post-thrombectomy staining becomes visible
In 12 patients after mechanical thrombectomy, 54 ASPECTS regions ultimately developed infarction; 40/54 (74.1%) showed hyperattenuation on PCCT iodine maps, but only 15/40 (37.5%) were visually hyperattenuating on conventional brain-window images. Thus, iodine accumulation was frequently measurable before becoming visually…
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(2025) Mark | 用于库欣病的 PCCT：病灶定位、术中发现及治疗结果
在连续接受经蝶手术的 25 名库欣病患者中，动态垂体 PCCT 对促肾上腺皮质激素细胞腺瘤的定位准确度显著高于术前 MRI：分别为 92% 和 56%（p = .01）。PCCT 在 25 名患者中的 24 名检出病灶，仅有 1 例定位有误。 在 MRI 未发现病灶或定位有误的病例中，这一优势尤为明显。25 名患者中有 20 名接受了影像引导下的靶向切除；其中 6 例手术靶点完全依据 PCCT 确定，可能避免了更广泛的垂体腺探查或次全切除。 临床结局令人鼓舞：平均随访 5.8 个月时，84% 的患者仍处于生化缓解状态，且未报告新发全垂体功能减退或中枢性尿崩症。不过，这是一项样本量较小、回顾性、非盲法的单中心研究，因此目前应将 PCCT 视为…
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(2026) Limantoro | Ultra-low dose pediatric chest PCCT approaching chest radiograph doses
In this feasibility study, an ultra-low-dose pediatric chest PCCT protocol was optimized to Sn100 kVp, 2 mAs, pitch 1.5, achieving a phantom effective dose of 14 µSv. In clinical use, the median total effective dose was 11.6 µSv, close to the 8.2 µSv median dose of a single chest radiograph. The protocol was applied in 24…
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(2025) Opitz | First assessment of photon-counting CT for virtual bronchoscopic navigation
In 40 patients (20 PCCT vs 20 BMI- and sex-matched EID-CT), PCCT successfully provided the high-resolution datasets required for virtual bronchoscopic navigation (VBN) and could be transferred into the navigation system for procedural planning. PCCT achieved an approximately 5–6× radiation-dose reduction: CTDIvol 1.5 vs…
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(2024) Dettmer | Chest X-ray–dose PCCT changes diagnosis in suspected pneumonia
In 27 adults with suspected respiratory infection, an ultra-low-dose PCCT chest protocol achieved a mean effective dose of 0.11 ± 0.04 mSv, essentially matching the German reference dose for a two-view chest radiograph. Despite this very low exposure, PCCT provided substantially more diagnostic information than…
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(2023) van der Bie | PCCT for TAVR planning and follow-up
This early case series illustrates how UHR PCCT can improve structural heart imaging before and after TAVR, particularly through sharper depiction of the aortic valve, annulus, coronary arteries, prosthetic valve frames, and vascular access routes. UHR acquisition allows 0.2-mm sections, compared with 0.4 mm in the regular…
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(2023) Turrion Gomollon | VNI PCCT may replace true noncontrast after EVAR
In 110 patients undergoing EVAR surveillance, including 41 endoleaks, the authors compared conventional triphasic PCCT (true noncontrast + arterial + venous) with a biphasic strategy in which virtual noniodine (VNI) images reconstructed from the venous phase replaced the true noncontrast acquisition. Endoleak detection was…
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(2024) Qin | Improvement of coronary stent visualization using UHR PCCT
In 69 patients with 131 coronary stents, UHR PCCT with 0.2-mm slices significantly improved in-stent lumen visualization and reduced blooming artifacts compared with standard-resolution 0.6-mm reconstruction. Among the evaluated reconstruction kernels, Bv72 provided the best overall performance, improving visualization of…
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(2026) Kabakus | Is nitroglycerin still necessary for CCTA in the era of PCCT?
In 124 patients with CCTA and invasive coronary angiography (ICA) within 30 days, diagnostic performance of PCCT CCTA was similar with and without sublingual nitroglycerin. Per-patient sensitivity was 90.3% vs 90.9%, and NPV was 86.4% vs 88.9%, with no significant differences between groups. The non-nitroglycerin group was…
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(2026) McCollough & Yu | CT Radiation Dose Reduction With Preserved Diagnostic Performance
Access publication Key message Over roughly 25 years, combined advances in CT hardware, acquisition, and reconstruction have enabled approximately 2- to 10-fold radiation-dose reductions, but dose reduction should be judged against preserved diagnostic performance, not merely lower image noise. Practical implication: Dose…
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(2023) Vattay | VMI energy substantially alters PCCT coronary plaque quantification
In 51 patients with 51 coronary plaques, PCCT VMI energy had a substantial effect on measured plaque attenuation and consequently on quantitative plaque composition when fixed HU thresholds were used. Mean plaque attenuation fell progressively from 723 ± 501 HU at 40 keV to 120 ± 112 HU at 180 keV, while 70-keV VMI most…
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(2026) Schwartz | Mixed-bolus low-keV PCCT improves CTPA robustness
In 150 patients undergoing PCCT pulmonary angiography, the investigators compared three contrast-injection strategies while reconstructing images at 40, 55, and 67 keV. Pulmonary arterial enhancement increased progressively at lower energies, with 40 keV providing the strongest vascular enhancement and highest reader…
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(2026) Tateishi | PCCT depicts a ventricular tachycardia substrate
The case report hase been published by: Tateishi, R, Nishimura, T, Tao, S. et al. Photon-Counting Detector Computed Tomography Depicts a Ventricular Tachycardia Substrate: Periaortic Septal Intramural Late Iodine Enhancement. J Am Coll Cardiol Case Rep. 2026 Apr, 31 (15) . https://doi.org/10.1016/j.jaccas.2026.107250 Check…
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(2022) Lennartz | Virtual unenhanced images show limitations for adrenal adenoma characterization
PCCT-derived virtual unenhanced (VUE) images showed no significant difference in mean attenuation compared with true unenhanced (TUE) images for adrenal adenomas (9.2 ± 8.6 HU vs 7.3 ± 8.4 HU; P = .07). Despite similar mean values, individual VUE measurements showed both over- and underestimation, resulting in 10 of 36…
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(2025) Hartung | Ultra-high vs Standard Resolution PCCT Angiography for Imaging of Femoral Stents
Ultra-high-resolution (UHR) PCCT provided better subjective image quality than standard-resolution (SR) PCCT for femoral stent CTA, while stent-lumen visibility itself remained comparable between modes. The study used a perfused human cadaveric upper-leg model with 7 superficial femoral artery stents. SR and UHR…
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(2024) Hagar | UHR PCCT accurately evaluates coronary stent patency
In 18 patients with 44 coronary stents, ultra-high-resolution (UHR) PCCT angiography achieved high diagnostic accuracy for detecting ≥50% in-stent stenosis compared with invasive coronary angiography (ICA). Both readers identified all 5 stenotic stents, yielding 100% sensitivity. Specificity and overall accuracy were 92.3%…
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(2024) Haag | PURE Calcium PCCT may replace true noncontrast calcium scoring
In 170 patients, coronary artery calcium scores derived from PCCT PureCalcium virtual noncontrast images showed excellent correlation with true noncontrast (TNC) calcium scoring (ICC 0.98). Median Agatston scores were not significantly different: 4.8 vs 2.7, respectively (p = 0.99). High correlation did not translate into…
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(2024) Gnasso | Optimized PCCT reconstruction improves myocardial ECV accuracy
In 27 patients undergoing same-day PCCT and cardiac MRI, myocardial extracellular volume (ECV) measurements remained robust across a wide range of reconstruction settings, but reconstruction choices meaningfully affected agreement with MRI. The greatest improvement came from combining thin slices with low-keV VMI, rather…
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(2024) Fink | Safety-net PCCT VNC improves subtle coronary calcium detection
Standard PCCT virtual noncontrast (VNC) calcium scoring performs well for larger and denser plaques but can miss subtle disease. Large/medium and high/medium-density plaques showed strong agreement with true noncontrast (TNC) scoring (r > 0.9; ICC ≥ 0.90), whereas low-density plaques showed poor agreement and small plaques…
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(2022) Emrich | CCTA-based calcium scoring with virtual noniodine PCCT
Evaluated whether coronary artery calcium scoring (CACS) can be derived directly from contrast-enhanced CCTA using the PCCT-specific PureCalcium virtual noniodine reconstruction, potentially eliminating the separate true noncontrast (TNC) calcium-score acquisition. Tested on a first-generation dual-source photon-counting…
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(2024) Augustin | Sharp-kernel PCCT improves lower-extremity CTA vs DSA
In 39 patients with 45 lower-extremity run-off studies, PCCT angiography was compared directly with digital subtraction angiography (DSA) for peripheral arterial occlusive disease. The cohort was challenging, with 77.8% of studies representing Fontaine stage IV disease, making severe calcification and small crural vessels…
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(2023) Aquino | PCCT ECV mapping correlates strongly with cardiac MRI
In this prospective same-day comparison of 29 patients, myocardial extracellular volume (ECV) measured with PCCT showed strong agreement with cardiac MRI, supporting spectral PCCT as a quantitative tool for myocardial tissue characterization. Dual-energy PCCT achieved correlations of r = 0.91 for global ECV and r = 0.82…
