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(2026) Huijberts | PCCTを用いたレンズ核線条体動脈の描出
この後ろ向きコホートでは、くも膜下出血患者159人を対象に、UHR PCCTは従来のEID-CTAと比べてレンズ核線条体動脈（LSA）の描出を大幅に改善しました。MCA起始部から5 mmを超えて分岐する枝では、PCCTの検出率はDSAに近づきました。たとえば、左半球における観察者1の検出率は93%対85%でした（p = 0.62）。一方、対応のない比較ではEID-CTAの検出率はわずか49%でした。 PCCTは、より太いLSA枝の末梢までの全長の描出ではDSAに及びませんでした。MCA起始部から5 mmを超えるLSAの長さの中央値は、観察者1でPCCTでは23 mm、DSAでは40…
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(2026) Hellms | ゲーティングなしの小児心臓PCCTは、画質を保ちながら被ばくを低減
先天性心疾患のある小児37人を、水等価径で対応させたEID-CT対照群37人と比較したところ、非ECG同期の高ピッチPCCTにより、放射線被ばくが大幅に低減した：CTDIvolは0.20 ± 0.12対0.37 ± 0.17 mGy、DLPは4.06 ± 3.22対7.21 ± 4.67 mGy·cmであり（いずれもp < 0.001）、それぞれ約46%、44%の低減に相当した。 被ばく線量が低いにもかかわらず、SNR、CNR、ビームハードニングアーチファクト、総合的な主観的画質、および近位冠動脈の描出に、PCCTとEID-CTとの有意差は認められなかった。これは、70 kV、ピッチ3.2の超高速・非ECG同期PCCT撮影によって実現した。…
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(2026) Volovici | 脳神経外科ナビゲーションのためのUHR PCCT純血管腔イメージング
複雑な脳神経外科症例20例を選択した本パイロットコホートでは、UHR PCCTにより従来のMRI/CTを超える追加の解剖学的情報が得られた。特に、動脈解剖（11/20、55%）、腫瘍の血流供給（7/20、35%）、静脈解剖（6/20、30%）、頭蓋底・眼窩・骨への浸潤（8/20、40%）で有用だった。最も有用と考えられたのは、複雑な頭蓋底髄膜腫および血管病変であった。 技術的な優位性は、0.2…
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A massive primary cerebral ALK-positive anaplastic large cell lymphoma in an adolescent
Xiangyu Liu, RT*; Jiaxu Wei, RT*; Xi Zhao, MD**; Ji Wang, RT* * Department of Radiology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, P. R. China** Siemens Healthineers, China 2025-07-02 Download pdf History A 15-year-old male patient, complaining of a growing lump on the right of…
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(2026) Nishii | Optimization of the kernel for temporal bone imaging in PCCT
This study combined physical phantom testing of 11 UHR reconstruction kernels (Hr60–Hr98) with clinical visual assessment in 12 patients / 24 temporal bones. Physically, increasing kernel sharpness improved spatial resolution but increased high-frequency noise: Hr96 achieved the highest measured resolution, whereas Hr60…
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PCCT for coronary assessment and functional imaging in Takotsubo cardiomyopathy
@Bálint Szilveszter, Borbála Vattay, Péter Csongor, @Milan Vecsey-Nagy Városmajor Heart and Vascular Centre, Cardiac CT Working Group, Budapest, Hungary September 29, 2026 https://siemens-healthineers.bynder.com/asset/a85e1bdc-bf2b-4a4d-94a0-dc890f0a7651/CT-NAEOTOM-CONNECT-CaseReport-Takutsobu-2-VIDEO-2026.mp4…
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PCCT for myocardial tissue characterization in acute myocarditis: comparison with CMR
Ferenc Imre Suhai, Barbara Sipos, Milán Vecsey-Nagy, Bálint Szilveszter Városmajor Heart and Vascular Centre, Cardiac CT Working Group, Budapest, Hungary September 29, 2026 https://siemens-healthineers.bynder.com/asset/2a67d11b-415e-4e25-a74a-42d82ff7a4d5/CT-NAEOTOM-CONNECT-CaseReport-BalintMyocard-1-VIDEO-2026.mp4…
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(2026) Hyska | Time-resolved PCCT estimates post-TAVI pressure gradients
In 71 post-TAVI PCCT examinations from 63 patients, time-resolved cardiac PCCT enabled calculation of prosthetic-valve hemodynamics from left-ventricular volumetry and direct valve-orifice planimetry. CT-derived mean and maximum transvalvular gradients correlated strongly with echocardiography (ρ = 0.85 for both), while…
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(2026) Pali | PCCT iodine maps quantify when post-thrombectomy staining becomes visible
In 12 patients after mechanical thrombectomy, 54 ASPECTS regions ultimately developed infarction; 40/54 (74.1%) showed hyperattenuation on PCCT iodine maps, but only 15/40 (37.5%) were visually hyperattenuating on conventional brain-window images. Thus, iodine accumulation was frequently measurable before becoming visually…
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(2025) Mark | クッシング病に対するPCCT：病変の局在診断、術中所見、転帰
経蝶形骨洞手術を受けたクッシング病患者25人を連続して調べたところ、動的下垂体PCCTは術前MRIよりもはるかに高い精度で副腎皮質刺激ホルモン産生腺腫の位置を特定しました（それぞれ92%対56%、p = .01）。PCCTは25人中24人で病変を検出し、誤解を招く位置特定は1例のみでした。 MRIで病変が確認できない、または誤った位置に病変が示された症例で、特に有用でした。画像に基づく標的切除は25人中20人に実施され、6例ではPCCTのみを根拠に手術標的を決定したため、より広範な下垂体の探索や亜全摘を回避できた可能性があります。…
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(2026) Limantoro | Ultra-low dose pediatric chest PCCT approaching chest radiograph doses
In this feasibility study, an ultra-low-dose pediatric chest PCCT protocol was optimized to Sn100 kVp, 2 mAs, pitch 1.5, achieving a phantom effective dose of 14 µSv. In clinical use, the median total effective dose was 11.6 µSv, close to the 8.2 µSv median dose of a single chest radiograph. The protocol was applied in 24…
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(2025) Opitz | First assessment of photon-counting CT for virtual bronchoscopic navigation
In 40 patients (20 PCCT vs 20 BMI- and sex-matched EID-CT), PCCT successfully provided the high-resolution datasets required for virtual bronchoscopic navigation (VBN) and could be transferred into the navigation system for procedural planning. PCCT achieved an approximately 5–6× radiation-dose reduction: CTDIvol 1.5 vs…
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(2024) Dettmer | Chest X-ray–dose PCCT changes diagnosis in suspected pneumonia
In 27 adults with suspected respiratory infection, an ultra-low-dose PCCT chest protocol achieved a mean effective dose of 0.11 ± 0.04 mSv, essentially matching the German reference dose for a two-view chest radiograph. Despite this very low exposure, PCCT provided substantially more diagnostic information than…
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(2023) van der Bie | PCCT for TAVR planning and follow-up
This early case series illustrates how UHR PCCT can improve structural heart imaging before and after TAVR, particularly through sharper depiction of the aortic valve, annulus, coronary arteries, prosthetic valve frames, and vascular access routes. UHR acquisition allows 0.2-mm sections, compared with 0.4 mm in the regular…
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(2023) Turrion Gomollon | VNI PCCT may replace true noncontrast after EVAR
In 110 patients undergoing EVAR surveillance, including 41 endoleaks, the authors compared conventional triphasic PCCT (true noncontrast + arterial + venous) with a biphasic strategy in which virtual noniodine (VNI) images reconstructed from the venous phase replaced the true noncontrast acquisition. Endoleak detection was…
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(2024) Qin | Improvement of coronary stent visualization using UHR PCCT
In 69 patients with 131 coronary stents, UHR PCCT with 0.2-mm slices significantly improved in-stent lumen visualization and reduced blooming artifacts compared with standard-resolution 0.6-mm reconstruction. Among the evaluated reconstruction kernels, Bv72 provided the best overall performance, improving visualization of…
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(2026) Kabakus | PCCT時代にCCTAでニトログリセリンはまだ必要か？
30日以内にCCTAと侵襲的冠動脈造影（ICA）を受けた124例において、PCCTによるCCTAの診断能は、舌下ニトログリセリンの使用の有無で同程度だった。患者単位の感度は90.3%対90.9%、NPVは86.4%対88.9%で、群間に有意差は認められなかった。 ニトログリセリン非投与群では、特異度（80.0%対63.3%）、PPV（83.3%対71.8%）、正診率（85.7%対77.0%）など複数の診断指標が数値上は良好だったが、いずれも統計的有意差には至らなかった。同様に、LAD、LCx、RCAの各解析でも有意差は認められず、これらの知見は診療を変えるものではなく、仮説を提示する段階にとどまる。…
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(2026) McCollough & Yu | CT Radiation Dose Reduction With Preserved Diagnostic Performance
Access publication Key message Over roughly 25 years, combined advances in CT hardware, acquisition, and reconstruction have enabled approximately 2- to 10-fold radiation-dose reductions, but dose reduction should be judged against preserved diagnostic performance, not merely lower image noise. Practical implication: Dose…
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(2023) Vattay | VMI energy substantially alters PCCT coronary plaque quantification
In 51 patients with 51 coronary plaques, PCCT VMI energy had a substantial effect on measured plaque attenuation and consequently on quantitative plaque composition when fixed HU thresholds were used. Mean plaque attenuation fell progressively from 723 ± 501 HU at 40 keV to 120 ± 112 HU at 180 keV, while 70-keV VMI most…
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(2026) Schwartz | Mixed-bolus low-keV PCCT improves CTPA robustness
In 150 patients undergoing PCCT pulmonary angiography, the investigators compared three contrast-injection strategies while reconstructing images at 40, 55, and 67 keV. Pulmonary arterial enhancement increased progressively at lower energies, with 40 keV providing the strongest vascular enhancement and highest reader…
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(2026) Tateishi | PCCT depicts a ventricular tachycardia substrate
The case report hase been published by: Tateishi, R, Nishimura, T, Tao, S. et al. Photon-Counting Detector Computed Tomography Depicts a Ventricular Tachycardia Substrate: Periaortic Septal Intramural Late Iodine Enhancement. J Am Coll Cardiol Case Rep. 2026 Apr, 31 (15) . https://doi.org/10.1016/j.jaccas.2026.107250 Check…
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(2022) Lennartz | Virtual unenhanced images show limitations for adrenal adenoma characterization
PCCT-derived virtual unenhanced (VUE) images showed no significant difference in mean attenuation compared with true unenhanced (TUE) images for adrenal adenomas (9.2 ± 8.6 HU vs 7.3 ± 8.4 HU; P = .07). Despite similar mean values, individual VUE measurements showed both over- and underestimation, resulting in 10 of 36…
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(2025) Hartung | Ultra-high vs Standard Resolution PCCT Angiography for Imaging of Femoral Stents
Ultra-high-resolution (UHR) PCCT provided better subjective image quality than standard-resolution (SR) PCCT for femoral stent CTA, while stent-lumen visibility itself remained comparable between modes. The study used a perfused human cadaveric upper-leg model with 7 superficial femoral artery stents. SR and UHR…
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(2024) Hagar | UHR PCCT accurately evaluates coronary stent patency
In 18 patients with 44 coronary stents, ultra-high-resolution (UHR) PCCT angiography achieved high diagnostic accuracy for detecting ≥50% in-stent stenosis compared with invasive coronary angiography (ICA). Both readers identified all 5 stenotic stents, yielding 100% sensitivity. Specificity and overall accuracy were 92.3%…
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(2024) Haag | PURE Calcium PCCT may replace true noncontrast calcium scoring
In 170 patients, coronary artery calcium scores derived from PCCT PureCalcium virtual noncontrast images showed excellent correlation with true noncontrast (TNC) calcium scoring (ICC 0.98). Median Agatston scores were not significantly different: 4.8 vs 2.7, respectively (p = 0.99). High correlation did not translate into…
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(2024) Gnasso | Optimized PCCT reconstruction improves myocardial ECV accuracy
In 27 patients undergoing same-day PCCT and cardiac MRI, myocardial extracellular volume (ECV) measurements remained robust across a wide range of reconstruction settings, but reconstruction choices meaningfully affected agreement with MRI. The greatest improvement came from combining thin slices with low-keV VMI, rather…
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(2024) Fink | Safety-net PCCT VNC improves subtle coronary calcium detection
Standard PCCT virtual noncontrast (VNC) calcium scoring performs well for larger and denser plaques but can miss subtle disease. Large/medium and high/medium-density plaques showed strong agreement with true noncontrast (TNC) scoring (r > 0.9; ICC ≥ 0.90), whereas low-density plaques showed poor agreement and small plaques…
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(2022) Emrich | CCTA-based calcium scoring with virtual noniodine PCCT
Evaluated whether coronary artery calcium scoring (CACS) can be derived directly from contrast-enhanced CCTA using the PCCT-specific PureCalcium virtual noniodine reconstruction, potentially eliminating the separate true noncontrast (TNC) calcium-score acquisition. Tested on a first-generation dual-source photon-counting…
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(2024) Augustin | Sharp-kernel PCCT improves lower-extremity CTA vs DSA
In 39 patients with 45 lower-extremity run-off studies, PCCT angiography was compared directly with digital subtraction angiography (DSA) for peripheral arterial occlusive disease. The cohort was challenging, with 77.8% of studies representing Fontaine stage IV disease, making severe calcification and small crural vessels…
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(2023) Aquino | PCCT ECV mapping correlates strongly with cardiac MRI
In this prospective same-day comparison of 29 patients, myocardial extracellular volume (ECV) measured with PCCT showed strong agreement with cardiac MRI, supporting spectral PCCT as a quantitative tool for myocardial tissue characterization. Dual-energy PCCT achieved correlations of r = 0.91 for global ECV and r = 0.82…
