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PCCT for coronary assessment and functional imaging in Takotsubo cardiomyopathy
@Bálint Szilveszter, Borbála Vattay, Péter Csongor, @Milan Vecsey-Nagy Városmajor Heart and Vascular Centre, Cardiac CT Working Group, Budapest, Hungary September 29, 2026 https://siemens-healthineers.bynder.com/asset/a85e1bdc-bf2b-4a4d-94a0-dc890f0a7651/CT-NAEOTOM-CONNECT-CaseReport-Takutsobu-2-VIDEO-2026.mp4…
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PCCT for myocardial tissue characterization in acute myocarditis: comparison with CMR
Ferenc Imre Suhai, Barbara Sipos, Milán Vecsey-Nagy, Bálint Szilveszter Városmajor Heart and Vascular Centre, Cardiac CT Working Group, Budapest, Hungary September 29, 2026 https://siemens-healthineers.bynder.com/asset/2a67d11b-415e-4e25-a74a-42d82ff7a4d5/CT-NAEOTOM-CONNECT-CaseReport-BalintMyocard-1-VIDEO-2026.mp4…
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(2026) Pali | PCCT iodine maps quantify when post-thrombectomy staining becomes visible
In 12 patients after mechanical thrombectomy, 54 ASPECTS regions ultimately developed infarction; 40/54 (74.1%) showed hyperattenuation on PCCT iodine maps, but only 15/40 (37.5%) were visually hyperattenuating on conventional brain-window images. Thus, iodine accumulation was frequently measurable before becoming visually…
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(2023) Turrion Gomollon | VNI PCCT may replace true noncontrast after EVAR
In 110 patients undergoing EVAR surveillance, including 41 endoleaks, the authors compared conventional triphasic PCCT (true noncontrast + arterial + venous) with a biphasic strategy in which virtual noniodine (VNI) images reconstructed from the venous phase replaced the true noncontrast acquisition. Endoleak detection was…
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(2026) Kabakus | Is nitroglycerin still nevessary for CCTA in the era of PCCT?
In 124 patients with CCTA and invasive coronary angiography (ICA) within 30 days, diagnostic performance of PCCT CCTA was similar with and without sublingual nitroglycerin. Per-patient sensitivity was 90.3% vs 90.9%, and NPV was 86.4% vs 88.9%, with no significant differences between groups. The non-nitroglycerin group was…
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(2026) Schwartz | Mixed-bolus low-keV PCCT improves CTPA robustness
In 150 patients undergoing PCCT pulmonary angiography, the investigators compared three contrast-injection strategies while reconstructing images at 40, 55, and 67 keV. Pulmonary arterial enhancement increased progressively at lower energies, with 40 keV providing the strongest vascular enhancement and highest reader…
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(2022) Lennartz | Virtual unenhanced images show limitations for adrenal adenoma characterization
PCCT-derived virtual unenhanced (VUE) images showed no significant difference in mean attenuation compared with true unenhanced (TUE) images for adrenal adenomas (9.2 ± 8.6 HU vs 7.3 ± 8.4 HU; P = .07). Despite similar mean values, individual VUE measurements showed both over- and underestimation, resulting in 10 of 36…
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(2024) Haag | PURE Calcium PCCT may replace true noncontrast calcium scoring
In 170 patients, coronary artery calcium scores derived from PCCT PureCalcium virtual noncontrast images showed excellent correlation with true noncontrast (TNC) calcium scoring (ICC 0.98). Median Agatston scores were not significantly different: 4.8 vs 2.7, respectively (p = 0.99). High correlation did not translate into…
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(2024) Gnasso | Optimized PCCT reconstruction improves myocardial ECV accuracy
In 27 patients undergoing same-day PCCT and cardiac MRI, myocardial extracellular volume (ECV) measurements remained robust across a wide range of reconstruction settings, but reconstruction choices meaningfully affected agreement with MRI. The greatest improvement came from combining thin slices with low-keV VMI, rather…
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(2024) Fink | Safety-net PCCT VNC improves subtle coronary calcium detection
Standard PCCT virtual noncontrast (VNC) calcium scoring performs well for larger and denser plaques but can miss subtle disease. Large/medium and high/medium-density plaques showed strong agreement with true noncontrast (TNC) scoring (r > 0.9; ICC ≥ 0.90), whereas low-density plaques showed poor agreement and small plaques…
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(2024) Augustin | Sharp-kernel PCCT improves lower-extremity CTA vs DSA
In 39 patients with 45 lower-extremity run-off studies, PCCT angiography was compared directly with digital subtraction angiography (DSA) for peripheral arterial occlusive disease. The cohort was challenging, with 77.8% of studies representing Fontaine stage IV disease, making severe calcification and small crural vessels…
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(2023) Aquino | PCCT ECV mapping correlates strongly with cardiac MRI
In this prospective same-day comparison of 29 patients, myocardial extracellular volume (ECV) measured with PCCT showed strong agreement with cardiac MRI, supporting spectral PCCT as a quantitative tool for myocardial tissue characterization. Dual-energy PCCT achieved correlations of r = 0.91 for global ECV and r = 0.82…
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(2023) Schade | Pseudoenhancement of renal cysts on PCCT
In 86 patients with 160 non-enhancing renal cysts, the study assessed how PCCT virtual monoenergetic image (VMI) energy level affects apparent renal cyst enhancement and therefore lesion classification. Low-keV VMI substantially increased apparent cyst attenuation: mean attenuation rose from 4 ± 11 HU at 190 keV to 36 ± 17…
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(2025) Dang | Low-dose 70 kV vs 120kV PCCT for infant cardiac imaging
In 58 infants <10 kg, cardiac PCCT at 70 kV and 120 kV provided comparable image quality, with similar aortic CNR and median subjective image-quality scores of 5/5 in both groups. 70 kV reduced radiation dose by almost 50%, with CTDI decreasing from 0.25 mGy at 120 kV to 0.13 mGy at 70 kV (P<0.001). The key trade-off is…
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(2026) Habib Geryes | Pediatric PCCT protocols and radiation exposure
This multicenter retrospective study evaluated 6,464 PCCT examinations in 4,772 pediatric patients across three French institutions and provides practical acquisition/reconstruction protocols across ten body regions. The cohort had a mean age of 7.9 ± 5.5 years (4 days–17.9 years); nearly one-third of examinations involved…
