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(2026) Pali | PCCT iodine maps quantify when post-thrombectomy staining becomes visible
In 12 patients after mechanical thrombectomy, 54 ASPECTS regions ultimately developed infarction; 40/54 (74.1%) showed hyperattenuation on PCCT iodine maps, but only 15/40 (37.5%) were visually hyperattenuating on conventional brain-window images. Thus, iodine accumulation was frequently measurable before becoming visually…
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(2026) Tóth | Spectral black-blood PCCT for high-resolution carotid vessel wall imaging
A novel spectral black-blood CT (BBCT) reconstruction used the spectral information from PCCT to suppress intraluminal iodine from a routine single-phase CTA dataset, enabling high-resolution carotid vessel wall imaging without an additional scan, contrast administration, or dedicated acquisition. Compared with…
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(2025) Shami | Clinical PCCT to detect intra-plaque haemorrhage and thrombus in carotid plaques
This proof-of-concept study is described as the first clinical PCCT study to characterize high-risk human carotid plaque features in living patients, using histology from subsequent carotid endarterectomy as the reference. The cohort comprised 10 symptomatic patients. Spectral PCCT could differentiate multiple plaque…
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(2026) Schwartz | Streamlined PCCT myelography protocol for detection of CSF-venous fistulas
A streamlined PCCT myelography protocol enabled whole-spine evaluation at 0.2 × 0.1 mm resolution while limiting scanner time to approximately 15 minutes, making high-resolution CSF leak imaging feasible in a busy clinical setting. In 35 patients with previously inconclusive spine imaging, PCCT definitively identified a…
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(2026) Kirschfink | Cardiac PCCT reliably rules out LAA thrombus in acute ischemic stroke
Cardiac PCCT integrated directly into the acute stroke CT workflow achieved 96% diagnostic accuracy, 90% sensitivity, 97% specificity, and a particularly strong 99% negative predictive value for left atrial appendage (LAA) thrombus compared with TEE. The cardiac acquisition was added immediately after stroke CTA with only…
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(2026) Klüner | PCCT reduces radiation dose while improving SNR in pediatric head CT
PCCT achieved lower radiation dose and higher signal-to-noise ratio (SNR) than energy-integrating CT across pediatric head phantom models, demonstrating improved dose efficiency for neuroimaging. The greatest radiation dose reduction was observed in the 10-year-old phantom (9% lower CTDIvol at clinically relevant IQL 200),…
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(2026) Szum | Optimizing Acute Stroke Diagnostics with PCCT: Karolinska stroke protocol
mCTA as the default decision tool: Multiphase CTA replaces binary CTA/CTP thinking by providing sufficient flow dynamics and collateral information for most stroke patients, enabling fast, confident triage without routine perfusion imaging. Head‑to‑heart imaging in the acute phase: Extending the first arterial mCTA phase…
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(2024) Schwartz | PCCT myelography for CSF-venous fistula detection in SIH
PCCT improved CVF detection sensitivity without a significant specificity penalty. Across all three readers, sensitivity was significantly higher for PCCT myelography than for EID-CT myelography, while specificity did not differ significantly. The authors attribute the diagnostic gain mainly to much higher spatial…
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Follow-up on an endovascular coiling embolization of a ruptured intracranial aneurysm
Xiangyu Liu, RT*; Jiaxu Wei, RT*; Xi Zhao, MD**; Ji Wang, RT* * Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China** Siemens Healthineers, China 2025-08-06 Download pdf History A 59-year-old female patient, suffering from a sudden onset of headache with nausea…
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A massive primary cerebral ALK-positive anaplastic large cell lymphoma in an adolescent
Xiangyu Liu, RT*; Jiaxu Wei, RT*; Xi Zhao, MD**; Ji Wang, RT* * Department of Radiology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, P. R. China** Siemens Healthineers, China 2025-07-02 Download pdf History A 15-year-old male patient, complaining of a growing lump on the right of…
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Follow up on an unruptured intracranial aneurysm treated with a flow diverter
Jiaxu Wei, RT*; Xiao Li, MD*; Huilin Zhao, MD*; Shenghao Ding, MD**; Lang Liu, MD**; Xi Zhao, MD***; Yan Zhou, MD* * Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China** Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University School of…
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Cerebrospinal fluid-venous fistula detected in a patient with a long history of headaches
Fides Regina Schwartz, MD; Timothy Amrhein, MD Department of Radiology, Duke University Health System, North Carolina, USA January 12, 2024 Download pdf Access the protocol History A 58-year-old female patient with a 10-year history of migraine, tinnitus and orthostatic headache, was referred to the department of…
